Judul: Antibody Responses to Avian Influenza Vaccination in Broiler Chicken in Indonesia

Penulis: E. Nugroho¹, R.D. Soejodono², T. Purnawarman², C. Basri², P. Hermans³, A.T. Muljono¹, G. Koch³ 

¹ Center for Indonesian Veterinary Analytical Studies (CIVAS), Jl. RSAU No. 4, Atang Sanjaya, Bogor, 16310, West Java, Indonesia.
² Department of Infectious Diseases and Veterinary Public Health, Faculty of Veterinary Medicine, Bogor Agricultural University, Jl Agatis, Kampus IPB Dramaga Bogor, 16680, West Java, Indonesia.
³ Central Veterinary Institute, part of Wageningen University and Research Centre, P.O. Box 65, 8200 Lelystad, The Netherlands. 

Summary/Abstract:

Avian Influenza (AI) is a highly infectious viral disease of poultry that continues to inflict severe economic damage to the poultry industry, particularly in countries in South East Asia. The objective of this study was to determine antibody titres after vaccination of broilers in the face of maternal antibodies. A total of 1.500 Cobb broiler chickens were divided at random into 5 groups of 300 chickens. Group 1 was vaccinated against AI on day 1, group 2 on day 7, group 3 on day 10, group 4 on day 14 of age, and group 5 was control and not vaccinated against AI. Samples collected were blood sample, tracheal swabs, and cloacal swabs. Serum samples were tested for H5 antibodies using HI test, tracheal and cloacal swabs were tested for rt-PCR. One-time vaccination of broiler chicken on day 1, 7, 10 or 14 with an inactivated H5N1 vaccine did not result in mean levels of antibody titers which are considered to be protective.

Citation: Nugroho E, Soejodono RD, Purnawarman T, Basri B, Hermans P, Muljono AT, Koch G.  2012. Antibody Responses to Avian Influenza Vaccination in Broiler Chicken in Indonesia. Poster Presented 8^th International Symposium on Avian Influenza. Royal Holloway University of London, 1-4 April 2012.